BDBM50453821 CHEMBL4206831
SMILES CCC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(Nc2ncc3N(C)C(=O)c4cc(C)ccc4N(C)c3n2)cc1
InChI Key InChIKey=KGXBCWANASZZQG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50453821
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant full length His-tagged human Aurora B expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in histone H3 phosphorylation at S10 residues after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair